(2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate

Base Information

• Chemical Name: (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate
• CAS No.: 1000866-32-9
• Molecular Formula: C₁₉H₃₀O₆
• Molecular Weight: 354.444
• Mol file: 1000866-32-9.mol

Synonyms:(2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate

Chemical Property of (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate

There total 9 articles about (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C29H40O6S2 (1000866-31-8) → (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate (1000866-32-9)

Guidance literature:

With hydrogen; nickel; In ethanol; at 80 ℃; for 8h;

DOI:10.1021/jo701885n

Reference yield: 70.0%

(2S,6S)-8-(benzyloxy)-6-methoxyoct-4-yn-2-yl (3,5-dimethoxyphenyl)acetate → (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate (1000866-32-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 12h; stereoselective reaction; Inert atmosphere;

DOI:10.3998/ark.5550190.p008.453

Reference yield:

C26H34O6 → (2S,6R)-8-hydroxy-6-methoxyoctan-2-yl (3,5-dimethoxyphenyl)acetate (1000866-32-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; for 10h;

DOI:10.1016/j.tetlet.2009.04.120

upstream raw materials:

C₂₉H₄₀O₆S₂

5-benzyloxy-2-pentyn-1-ol

(E)-5-(benzyloxy)pent-2-en-1-ol

((2S,3S)-3-(2-(benzyloxy)ethyl)oxiran-2-yl)methanol

Downstream raw materials:

(1S,5R)-6-carboxy-5-methoxy-1-methylhexyl 3,5-dimethoxybenzeneacetate