Chemical Property of Neoprotoveratrine
Chemical Property:
- Vapor Pressure:1.94E-33mmHg at 25°C
- Melting Point:268-270°C
- Refractive Index:1.6220 (estimate)
- Boiling Point:847.9°Cat760mmHg
- PKA:10.73±0.70(Predicted)
- Flash Point:466.6°C
- PSA：239.05000
- Density:1.39g/cm3
- LogP:0.51590
- Storage Temp.:2-8°C
- XLogP3:1
- Hydrogen Bond Donor Count:6
- Hydrogen Bond Acceptor Count:16
- Rotatable Bond Count:12
- Exact Mass:809.41977030
- Heavy Atom Count:57
- Complexity:1660
- Purity/Quality:
-
98%min *data from raw suppliers
PROTOVERATRINE B 95.00% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(C(C6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(C(C)O)O)O)C)OC(=O)C)OC(=O)C)O)O
- Isomeric SMILES:CC[C@@H](C)C(=O)O[C@H]1[C@@H]([C@H]2[C@@H](CN3C[C@H](CC[C@H]3[C@@]2(C)O)C)[C@H]4[C@@]1([C@@H]5[C@@H]([C@@H]([C@H]6[C@]7([C@]5(C4)O[C@]6([C@H](CC7)OC(=O)[C@@](C)([C@@H](C)O)O)O)C)OC(=O)C)OC(=O)C)O)O
-
Description
Also present in Veratrum album, this closely allied alkaloid may be separated
from the preceding base by chromatography. It also yields colourless crystals
from EtOH and is laevorotatory with [α]29D&o - 39.8° (pyridine) or - 3.5° (CHCI3).
In this case, alkaline hydrolysis gives protoverine, two moles of acetic acid, one
mole of (-)-2-methylbutyric acid and one mole of 2: 3-dihydroxy-2-
methylbutyric acid. It may be distinguished from protoveratrine A by giving a
green colour with H2S04. It also forms a complex with maleic acid having m.p.
222.2°C; [α]29D&o - 27.3°.
