4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide

Base Information

• Chemical Name: 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide
• CAS No.: 82859-76-5
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.261
• Mol file: 82859-76-5.mol

Synonyms:4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide

Chemical Property of 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-HYDROXYBENZOIC (2-HYDROXYBENZYLIDENE)HYDRAZIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide

There total 4 articles about 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

salicylaldehyde (90-02-8) + 4-hydroxybenzoic acid hydrazide (5351-23-5) → 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide (82859-76-5)

Guidance literature:

In ethanol; at 25 ℃; for 0.5h;

DOI:10.1007/s00044-016-1661-4

Reference yield: 80.0%

→ 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide (82859-76-5)

Guidance literature:

In ethanol; at 40 ℃;

Reference yield:

2-methyl-benzyl alcohol (89-95-2) + 4-hydroxybenzoic acid hydrazide (5351-23-5) → 4-hydroxy-N’-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide (82859-76-5)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2005.09.058

upstream raw materials:

salicylaldehyde

4-hydroxybenzoic acid hydrazide

2-methyl-benzyl alcohol

methyl 4-hydroxylbenzoate

Downstream raw materials:

[Cu((E)-N'-(2-hydroxybenzylidene)-4-(hydroxybenzohydrazide(-1H))(NO₃)](H₂O)

[(Cu((E)-N'-(2-hydroxybenzylidene)-4-(hydroxybenzohydrazide(-1H))(Me₂NCO))]2