3-(4-Tert-butoxyphenyl)-propan-1-ol

Base Information

Chemical Name:3-(4-Tert-butoxyphenyl)-propan-1-ol
CAS No.:132307-87-0
Molecular Formula:C₁₃H₂₀O₂
Molecular Weight:208.301
Hs Code.:
DSSTox Substance ID:DTXSID701287329

Synonyms:3-(4-tert-butoxyphenyl)-propan-1-ol;SCHEMBL3451212;MEEGORRTLJULSJ-UHFFFAOYSA-N;DTXSID701287329;4-(1,1-Dimethylethoxy)benzenepropanol;132307-87-0

Suppliers and Price of 3-(4-Tert-butoxyphenyl)-propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-Tert-butoxyphenyl)-propan-1-ol

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:208.146329876
Heavy Atom Count:15
Complexity:164

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC1=CC=C(C=C1)CCCO

Technology Process of 3-(4-Tert-butoxyphenyl)-propan-1-ol

There total 3 articles about 3-(4-Tert-butoxyphenyl)-propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₃₄O₂Si

: 132307-87-0
3-(4-tert-butoxyphenyl)-propan-1-ol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ja070063i

Reference yield:

: 106-44-5
p-cresol

: 132307-87-0
3-(4-tert-butoxyphenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 44 percent / H₂SO₄ / CH₂Cl₂ / 0.33 h / -15 °C

2.1: KOtBu; n-BuLi / tetrahydrofuran; hexane / 1 h / -15 °C

2.2: tetrahydrofuran; hexane / -15 - 20 °C

3.1: 6.60 g / TBAF / tetrahydrofuran / 20 °C

With n-butyllithium; sulfuric acid; potassium tert-butylate; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja070063i

Reference yield:

: 15359-98-5
4-(tert-butoxy)toluene

: 132307-87-0
3-(4-tert-butoxyphenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: KOtBu; n-BuLi / tetrahydrofuran; hexane / 1 h / -15 °C

1.2: tetrahydrofuran; hexane / -15 - 20 °C

2.1: 6.60 g / TBAF / tetrahydrofuran / 20 °C

With n-butyllithium; potassium tert-butylate; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane;
DOI:10.1021/ja070063i