(R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

Base Information

Chemical Name:(R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid
CAS No.:1073132-18-9
Molecular Formula:C₂₅H₂₇NO₈
Molecular Weight:469.491
Hs Code.:

Synonyms:(R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

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Chemical Property of (R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

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Technology Process of (R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

There total 1 articles about (R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1073132-17-8
(R)-4-benzyl-3-[2-((R)-2-benzyloxyethyl)-(S)-3-acetoxy-4-pentenoyl]oxazolidin-2-one

: 1073132-18-9
(R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

Guidance literature:: (R)-4-benzyl-3-[2-((R)-2-benzyloxyethyl)-(S)-3-acetoxy-4-pentenoyl]oxazolidin-2-one; With dimethylsulfide; ozone; In dichloromethane; at -78 - 20 ℃;

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In tetrahydrofuran; water; tert-butyl alcohol; at 0 - 20 ℃;

With hydrogenchloride; water; In tetrahydrofuran; tert-butyl alcohol; pH=1;
DOI:10.1021/jo801708q

Reference yield: 100.0%

: 1073132-18-9
(R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid

: 1073132-19-0
2-((R)-2-benzyloxyethyl)-(R)-3-hydroxysuccinic acid

Guidance literature:: (R)-2-acetoxy-(R)-3-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-benzyloxypentanoic acid; With lithium hydroxide; water; dihydrogen peroxide; In tetrahydrofuran; at 0 ℃; for 2h;

With hydrogenchloride; water; pH=1;
DOI:10.1021/jo801708q