((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

Base Information

Chemical Name:((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde
CAS No.:115095-75-5
Molecular Formula:C₁₃H₁₉NO₃
Molecular Weight:237.299
Hs Code.:

Synonyms:((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

Suppliers and Price of ((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of ((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

There total 1 articles about ((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73670-87-8
(E)-hexa-3,5-dien-1-ol

: 115095-75-5
((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / toluene / 24 h / Heating

In toluene;
DOI:10.1021/jo00251a049

Reference yield: 100.0%

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 115095-75-5
((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

: 115095-76-6,115095-77-7
(3R,3aS,7S,7aR)-3-Ethoxy-2-methyl-7-((E)-2-triisopropylsilanyloxy-vinyl)-2,3,3a,4,7,7a-hexahydro-isoindol-1-one

Guidance literature:: With triethylamine; In diethyl ether; at 20 ℃; for 19h;
DOI:10.1021/jo00251a049

Reference yield:

: 115095-75-5
((1S,3aS,4S,7aR)-1-Ethoxy-2-methyl-3-oxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-4-yl)-acetaldehyde

: 115095-86-8
C₂₀H₂₅NO₃

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / Et₃N / diethyl ether / 19 h / 20 °C

2: 1.) LDA / 1.) THF, -78 deg C, 30 min

3: 1.) SnCl₄, 2.) NaBH₄ / 1.) 0 to 20 deg C, 20 h

With sodium tetrahydroborate; tin(IV) chloride; triethylamine; lithium diisopropyl amide; In diethyl ether;
DOI:10.1021/jo00251a049