Niguldipine

Base Information

• Chemical Name: Niguldipine
• CAS No.: 102993-22-6
• Molecular Formula: C₃₆H₃₉N₃O₆
• Molecular Weight: 609.722
• UNII: 6Q39TPF0GL
• DSSTox Substance ID: DTXSID7048407
• Wikipedia: Niguldipine
• Wikidata: Q13566125
• NCI Thesaurus Code: C84018
• ChEMBL ID: CHEMBL1275655
• Mol file: 102993-22-6.mol

Synonyms:3-((4,4-diphenyl-1-piperidinyl)propyl)-5-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride;3-methyl-5-(3-(4,4-diphenyl-1-piperidinyl)propyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate;B 844-39;B 859-35;B8509-035;B859-35;dexniguldipine;DNIG;niguldipine;niguldipine fumarate;niguldipine hydrobromide;niguldipine hydrochloride;niguldipine maleate

Chemical Property of Niguldipine

Chemical Property:

• Vapor Pressure: 3.9E-21mmHg at 25°C
• Boiling Point: 729.5°Cat760mmHg
• PKA: 8.45±0.10(Predicted)
• Flash Point: 395°C
• PSA: 113.69000
• Density: 1.205g/cm³
• LogP: 6.80790
• XLogP3: 6.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 11
• Exact Mass: 609.28388597
• Heavy Atom Count: 45
• Complexity: 1100

Purity/Quality:

99% ^*data from raw suppliers

NIGULDIPINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCCCN2CCC(CC2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC

Technology Process of Niguldipine

There total 1 articles about Niguldipine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ niguldipine (113165-32-5,102993-22-6)

Guidance literature: