(2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Base Information

Chemical Name:(2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole
CAS No.:240821-01-6
Molecular Formula:C₂₄H₃₄O₃Si
Molecular Weight:398.618
Hs Code.:

Synonyms:(2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Suppliers and Price of (2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

There total 3 articles about (2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 240821-00-5
[4R,3(2R,3S,4R)]-3-(5-tert-butyldiphenylsilyloxy-3-hydroxy-4-methyl-2-vinylpentanoyl)-4-isopropyl-2-oxazolidinone

: 240821-01-6
(2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Guidance literature:: With lithium borohydride; water; In tetrahydrofuran; diethyl ether;
DOI:10.1055/s-1999-2730

Reference yield:

: 91751-24-5,92817-88-4,123284-89-9,112897-04-8
(R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal

: 240821-01-6
(2S,3S,4R)-5-tert-butyldiphenylsilyloxy-4-methyl-2-vinylpentane-1,3-diole

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / TiCl₄; iso-Pr₂EtN / CH₂Cl₂ / 3 h / 0 °C

2: LiBH₄ / tetrahydrofuran; diethyl ether / 0.5 h / 0 °C

3: aq. NaOH / diethyl ether

With sodium hydroxide; lithium borohydride; titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; 1: Condensation / 2: Reduction / 3: Hydrolysis;
DOI:10.1248/cpb.47.1288