Technology Process of iso-butyl sidechain acid
There total 5 articles about iso-butyl sidechain acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-N,2-O-anisaldehyde acetal-3-N-Cbz-5-methyl hexanoyl methyl ester;
With
lithium hydroxide; water;
In
ethanol;
at 20 ℃;
for 4.83333h;
With
hydrogenchloride;
In
water;
pH=1;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid / toluene / 2.5 h / Heating / reflux
2.1: lithium hydroxide; water / ethanol / 4.83 h / 20 °C
2.2: pH 1
With
lithium hydroxide; water; toluene-4-sulfonic acid;
In
ethanol; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / 4.5 h / 0 °C
1.2: 3 h / pH 8.5
2.1: toluene-4-sulfonic acid / toluene / 2.5 h / Heating / reflux
3.1: lithium hydroxide; water / ethanol / 4.83 h / 20 °C
3.2: pH 1
With
lithium hydroxide; thionyl chloride; water; toluene-4-sulfonic acid;
In
ethanol; toluene;
