C₆₆H₉₄N₈O₁₅

Base Information

• Chemical Name: C₆₆H₉₄N₈O₁₅
• CAS No.: 1224192-16-8
• Molecular Formula: C₆₆H₉₄N₈O₁₅
• Molecular Weight: 1239.52
• Mol file: 1224192-16-8.mol

Synonyms:C₆₆H₉₄N₈O₁₅

Chemical Property of C₆₆H₉₄N₈O₁₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₉₄N₈O₁₅

There total 1 articles about C₆₆H₉₄N₈O₁₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-fluoren-9-yl-methoxycarbonyl-N-benzyloxyethyl-glycine (1181208-31-0) + 1-amino-4-[(tert-butyloxycarbonyl)amino]butane (68076-36-8) + bromoacetic acid (79-08-3) → C66H94N8O15 (1224192-16-8)

Guidance literature:

N-fluoren-9-yl-methoxycarbonyl-N-benzyloxyethyl-glycine; With 2-chlorotrityl chloride polystyrene resin; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h; solid phase reaction;

With piperidine; In N,N-dimethyl-formamide;

N-fluoren-9-yl-methoxycarbonyl-N-benzyloxyethyl-glycine; 1-amino-4-[(tert-butyloxycarbonyl)amino]butane; bromoacetic acid; Further stages;

DOI:10.1016/j.bmc.2010.01.026

Reference yield: 100.0%

C66H94N8O15 (1224192-16-8) + trifluoroacetic acid (76-05-1) → 3C2HF3O2*C56H78N8O11

Guidance literature:

In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.bmc.2010.01.026

Reference yield: 57.0%

C66H94N8O15 (1224192-16-8) → C66H92N8O14 (1224192-20-4)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 14h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.01.026

upstream raw materials:

N-fluoren-9-yl-methoxycarbonyl-N-benzyloxyethyl-glycine

1-amino-4-[(tert-butyloxycarbonyl)amino]butane

bromoacetic acid

Downstream raw materials:

C₆₆H₉₂N₈O₁₄