2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

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Chemical Name:2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide
CAS No.:1429925-39-2
Molecular Formula:C₂₆H₃₈N₈O₂
Molecular Weight:494.64
Hs Code.:

Synonyms:2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

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Chemical Property of 2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

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Technology Process of 2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

There total 1 articles about 2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 1338681-43-8
[7-(3-chlorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetic acid

: (1S)-1-cyclohexyl-2-(4-methylpiperazin-1-yl)ethanamine trihydrochloride

: 1429925-39-2
2-[(4R)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

: 1429925-40-5
2-[(4S)-7-(2-aminopyrimidin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]-N-[(1S)-1-cyclohexyl-2-(4-methyl piperazin-1-yl)ethyl]acetamide

Guidance literature:: [7-(3-chlorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetic acid; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; for 0.25h;

(1S)-1-cyclohexyl-2-(4-methylpiperazin-1-yl)ethanamine trihydrochloride; In 1,4-dioxane; at 70 ℃; for 2h;