C₅₄H₆₅N₉O₇

Base Information

• Chemical Name: C₅₄H₆₅N₉O₇
• CAS No.: 1612854-18-8
• Molecular Formula: C₅₄H₆₅N₉O₇
• Molecular Weight: 952.166
• Mol file: 1612854-18-8.mol

Synonyms:C₅₄H₆₅N₉O₇

Chemical Property of C₅₄H₆₅N₉O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₄H₆₅N₉O₇

There total 25 articles about C₅₄H₆₅N₉O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

C26H35BN4O6 (1612854-16-6) + C35H42F3N5O6S (1612854-17-7) → C54H65N9O7 (1612854-18-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; water; at 90 ℃; for 3h; Inert atmosphere;

Reference yield:

4,7-dimethoxyindan-1-one (52428-09-8) → C54H65N9O7 (1612854-18-8)

Guidance literature:

Multi-step reaction with 6 steps

1: sodium hydride / N,N-dimethyl-formamide / 18 h / 0 - 50 °C / Inert atmosphere

2: trifluoroacetic acid; triethylsilane / 7 h / 0 - 40 °C / Inert atmosphere

3: hydrogen bromide; acetic acid / 12 h / Reflux

4: triethylamine / dichloromethane / 2 h / 0 - 20 °C

5: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 90 °C / Inert atmosphere

6: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 90 °C / Inert atmosphere

With triethylsilane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen bromide; sodium hydride; potassium carbonate; acetic acid; triethylamine; trifluoroacetic acid; In 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

3-(2,5-dimethoxyphenyl)propanoic acid (10538-49-5) → C54H65N9O7 (1612854-18-8)

Guidance literature:

Multi-step reaction with 7 steps

1: polyphosphoric acid / 4 h / 80 °C

2: sodium hydride / N,N-dimethyl-formamide / 18 h / 0 - 50 °C / Inert atmosphere

3: trifluoroacetic acid; triethylsilane / 7 h / 0 - 40 °C / Inert atmosphere

4: hydrogen bromide; acetic acid / 12 h / Reflux

5: triethylamine / dichloromethane / 2 h / 0 - 20 °C

6: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 90 °C / Inert atmosphere

7: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 3 h / 90 °C / Inert atmosphere

With triethylsilane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen bromide; sodium hydride; potassium carbonate; acetic acid; triethylamine; trifluoroacetic acid; In 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

2,5-dimethoxybenzaldehyde

3-(2,5-dimethoxyphenyl)propanoic acid

4,7-dimethoxyindan-1-one

(S)-tert-butyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate