benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

Base Information

Chemical Name:benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate
CAS No.:1361391-69-6
Molecular Formula:C₂₅H₂₆N₆O₃S
Molecular Weight:490.586
Hs Code.:

Synonyms:benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

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Chemical Property of benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

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Technology Process of benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

There total 3 articles about benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 64001-11-2
1-(4-hydroxyphenyl)-1H-1,2,3,4-tetrazole

: 1361391-73-2
benzyl 4-(4-(chloromethyl)thiazol-2-yl)cyclohexylcarbamate

: 1361391-69-6
benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

Guidance literature:: With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

Reference yield:

: 1361391-71-0
benzyl 4-carbamothioylcyclohexylcarbamate

: 1361391-69-6
benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: magnesium sulfate / acetone / 5 h / Reflux

2: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 80 °C

With magnesium sulfate; potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; acetone;

Reference yield:

: 1361391-70-9
benzyl 4-cyanocyclohexylcarbamate

: 1361391-69-6
benzyl 4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)thiazol-2-yl)cyclohexylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; O,O-Diethyl hydrogen phosphorodithioate / 1,4-dioxane / 2.5 h / 0 - 20 °C

2: magnesium sulfate / acetone / 5 h / Reflux

3: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / 80 °C

With hydrogenchloride; magnesium sulfate; potassium carbonate; O,O-Diethyl hydrogen phosphorodithioate; potassium iodide; In 1,4-dioxane; N,N-dimethyl-formamide; acetone;