roivacaine

Base Information

• Chemical Name: roivacaine
• CAS No.: 175888-75-2
• Molecular Formula: C₁₇H₂₆N₂O
• Molecular Weight: 274.406
• Mol file: 175888-75-2.mol

Synonyms:roivacaine

Chemical Property of roivacaine

Chemical Property:

• Boiling Point: 404.7±45.0 °C(Predicted)
• Density: 1.052±0.06 g/cm3(Predicted)

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of roivacaine

There total 1 articles about roivacaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2',6'-pipecoloxylidide (27262-40-4) + isopropyl alcohol (67-63-0,8013-70-5) → roivacaine (175888-75-2) + 2',6'-pipecoloxylidide (15883-20-2,27262-40-4,27262-43-7,78341-12-5)

Guidance literature:

With Shvo catalyst; In dibutyl ether; at 140 ℃; for 2h; Inert atmosphere;

DOI:10.1021/op200268h

Reference yield:

roivacaine (175888-75-2) → roivacaine (1050482-18-2) + roivacaine (265120-58-9)

Guidance literature:

With chiral stationary phase derived from aminated silica gel, (1S,2R)-1,2-diphenyl-2-(3-phenylureido)ethyl 4-isocyanatophenylcarbamate and two-generation dendrimer; In water; acetonitrile; at 25 ℃; Resolution of racemate;

DOI:10.1002/chir.20708

upstream raw materials:

(S)-2',6'-pipecoloxylidide

isopropyl alcohol

Downstream raw materials:

roivacaine

roivacaine