Diethyl 8-Deazaaminopterin

Base Information

Chemical Name:Diethyl 8-Deazaaminopterin
CAS No.:76807-59-5
Molecular Formula:C₂₄H₂₉N₇O₅
Molecular Weight:495.538
Hs Code.:

Synonyms:Diethyl 8-Deazaaminopterin

Suppliers and Price of Diethyl 8-Deazaaminopterin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Diethyl 8-Deazaaminopterin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Diethyl 8-Deazaaminopterin

There total 7 articles about Diethyl 8-Deazaaminopterin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76807-55-1
6-(Acetoxymethyl)-2,4-dichloropyrido<3,2-d>pyrimidine

: 76807-59-5
Diethyl 8-Deazaaminopterin

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / liquid NH₃ / 18 h / 160 - 170 °C

2: PBr₃ / tetrahydrofuran / 8 h

3: N,N-dimethyl-acetamide / 72 h / Ambient temperature

With ammonia; phosphorus tribromide; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1021/jo00322a004

Reference yield:

: 76807-54-0
6-(Acetoxymethyl)-2,4-dioxopyrido<3,2-d>pyrimidine

: 76807-59-5
Diethyl 8-Deazaaminopterin

Guidance literature:: Multi-step reaction with 4 steps

1: 62 percent / POCl₃, (C₂H₅)3N / 8 h / Heating

2: 84 percent / liquid NH₃ / 18 h / 160 - 170 °C

3: PBr₃ / tetrahydrofuran / 8 h

4: N,N-dimethyl-acetamide / 72 h / Ambient temperature

With ammonia; phosphorus tribromide; triethylamine; trichlorophosphate; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1021/jo00322a004

Reference yield:

: 2499-96-9
2,4-Dioxo-6-methylpyrido<3,2-d>pyrimidine

: 76807-59-5
Diethyl 8-Deazaaminopterin

Guidance literature:: Multi-step reaction with 6 steps

1: 83 percent / m-Chloroperoxybenzoic acid / acetic acid / 3 h / Heating

2: 85 percent / acetic acid / 0.5 h / Heating

3: 62 percent / POCl₃, (C₂H₅)3N / 8 h / Heating

4: 84 percent / liquid NH₃ / 18 h / 160 - 170 °C

5: PBr₃ / tetrahydrofuran / 8 h

6: N,N-dimethyl-acetamide / 72 h / Ambient temperature

With ammonia; phosphorus tribromide; triethylamine; 3-chloro-benzenecarboperoxoic acid; trichlorophosphate; In tetrahydrofuran; N,N-dimethyl acetamide; acetic acid;
DOI:10.1021/jo00322a004