5-Amino-2-chlorobenzenesulfonic Acid

Base Information

• Chemical Name: 5-Amino-2-chlorobenzenesulfonic Acid
• CAS No.: 88-43-7
• Molecular Formula: C6H6 Cl N O3 S
• Molecular Weight: 207.638
• Hs Code.: 2921420090
• European Community (EC) Number: 201-830-8
• NSC Number: 15346
• UNII: P6W5Q8ZPN5
• DSSTox Substance ID: DTXSID2058968
• Nikkaji Number: J4.293E
• Wikidata: Q27286296
• Mol file: 88-43-7.mol

Synonyms:88-43-7;5-Amino-2-chlorobenzenesulfonic Acid;4-Chloroaniline-3-sulfonic acid;6-CHLOROMETANILIC ACID;Benzenesulfonic acid, 5-amino-2-chloro-;p-Chloroaniline-m-sulfonic acid;Metanilic acid, 6-chloro-;5-Amino-2-chlorobenzenesulphonic acid;5-amino-2-chlorobenzene-1-sulfonic acid;4-Chloro-3-sulfoaniline;UNII-P6W5Q8ZPN5;P6W5Q8ZPN5;HSDB 2566;EINECS 201-830-8;3-amino-6-chlorobenzenesulfonic acid;NSC 15346;NSC-15346;1-Amino-4-chlorobenzene-3-sulfonic acid;AI3-28528;2-chloro-5-aminobenzenesulfonic acid;4-CHLOROANILINE-3-SULFONICACID;SCHEMBL176866;5-amino-2-chlorbenzensulfonsyre;DTXSID2058968;5-Amino-2-chlorobenzenesulfonicAcid;NSC15346;MFCD00025296;AKOS015854640;4-amino-1-chlorobenzene-2-sulfonic acid;1-amino-4-chlorobenzene-3-sulphonic acid;AS-62714;CS-0188462;FT-0617962;4-CHLOROANILINE-3-SULFONIC ACID [HSDB];E78254;EN300-123556;A842584;W-100405;Q27286296;3-[[2-carboxyethyl(oxo)germyl]oxy-oxo-germyl]propanoic acid

Chemical Property of 5-Amino-2-chlorobenzenesulfonic Acid

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 280℃
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 290℃[at 101 325 Pa]
• PKA: -1.70±0.42(Predicted)
• PSA: 88.77000
• Density: 1.642g/cm³
• LogP: 2.83090
• Water Solubility.: 11.6g/L(0 oC)
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 206.9756919
• Heavy Atom Count: 12
• Complexity: 248

Purity/Quality:

98% ^*data from raw suppliers

4-Chloroaniline-3-sulfonic Acid >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Aminobenzenesulfonic Acids
• Canonical SMILES: C1=CC(=C(C=C1N)S(=O)(=O)O)Cl

Technology Process of 5-Amino-2-chlorobenzenesulfonic Acid

There total 9 articles about 5-Amino-2-chlorobenzenesulfonic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-aniline (106-47-8) → 4-chloroaniline-3-sulfonic acid (88-43-7) + 2-amino-5-chlorobenzenesulfonic acid (133-74-4)

Guidance literature:

With sulfuric acid;

Reference yield:

4-chloro-aniline (106-47-8) → 4-chloroaniline-3-sulfonic acid (88-43-7)

Guidance literature:

With sulfuric acid;

Reference yield:

N-(4-chlorophenyl)acetamide (539-03-7) → 4-chloroaniline-3-sulfonic acid (88-43-7)

Guidance literature:

With sulfuric acid; at 145 ℃;

DOI:10.1021/ja01860a050

upstream raw materials:

2-chloro-5-nitro-benzenesulfonic acid

4-chloro-aniline

N-(4-chlorophenyl)acetamide

sulfuric acid

Downstream raw materials:

C₁₅H₁₅Cl₂N₃O₇S₂

Refernces

• 1、 -. "2,4-diamino-6-fluorotriazine disazo reactive dyestuffs". . . Retrieved 2008/06/13.
• 2、 -. "Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge". . . Retrieved 2008/06/13.