(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione
CAS No.:1213254-32-0
Molecular Formula:C₂₄H₃₁N₅O₃
Molecular Weight:437.542
Hs Code.:

Synonyms:(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Suppliers and Price of (R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

There total 10 articles about (R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1213255-73-2
1-(hex-5-ynyl)pyrimidine-2,4(1H,3H)-dione

: 1213256-04-2
(R)-1-(1-azidobutan-2-yl)-3-(cyclopropylmethoxy)benzene

: 1213254-32-0
(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II); In 1,4-dioxane; at 80 ℃;
DOI:10.1021/jm3004174

Reference yield:

: C₂₀H₂₁NO₄

: 1213254-32-0
(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / methanol; N,N-dimethyl-formamide / 90 °C

2: lithium borohydride / tetrahydrofuran / 0 °C

3: triethylamine / dichloromethane / 20 °C

4: sodium azide / dichloromethane; N,N-dimethyl-formamide / 60 °C

5: chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II) / 1,4-dioxane / 80 °C

With lithium borohydride; sodium azide; chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II); potassium carbonate; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm3004174

Reference yield:

: C₁₅H₂₂O₄S

: 1213254-32-0
(R)-1-(4-(1-(2-(3-(cyclopropylmethoxy)phenyl)butyl)-1H-1,2,3-triazol-5-yl)butyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / dichloromethane; N,N-dimethyl-formamide / 60 °C

2: chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II) / 1,4-dioxane / 80 °C

With sodium azide; chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II); In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm3004174