1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene

Base Information

• Chemical Name: 1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene
• CAS No.: 1638098-17-5
• Molecular Formula: C₁₉H₂₃F₆N₅O₂
• Molecular Weight: 467.414
• Mol file: 1638098-17-5.mol

Synonyms:1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene

Chemical Property of 1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene

There total 1 articles about 1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2,2,2-trifluoroacetamide (354-38-1) + [3,5-bis(bromomethyl)-2,4,6-triethylphenyl]methyl azide (259268-22-9) → 1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene (1638098-17-5)

Guidance literature:

2,2,2-trifluoroacetamide; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.0833333h;

[3,5-bis(bromomethyl)-2,4,6-triethylphenyl]methyl azide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;

DOI:10.1002/chem.201400365

Reference yield: 97.0%

1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene (1638098-17-5) → 1,3-bis(aminomethyl)-5-azidomethyl-2,4,6-triethylbenzene (1638098-19-7)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃;

DOI:10.1002/chem.201400365

Reference yield:

1-azidomethyl-3,5-bis(trifluoroacetamidomethyl)-2,4,6-triethylbenzene (1638098-17-5) → C37H55N7O4 (1638098-21-1)

Guidance literature:

Multi-step reaction with 3 steps

1: water; sodium hydroxide / methanol / 20 °C

2: acetic acid / chloroform / 20 °C

3: sodium tetrahydroborate / chloroform; methanol / 1 h / 0 - 20 °C

With sodium tetrahydroborate; water; acetic acid; sodium hydroxide; In methanol; chloroform;

DOI:10.1002/chem.201400365

upstream raw materials:

2,2,2-trifluoroacetamide

[3,5-bis(bromomethyl)-2,4,6-triethylphenyl]methyl azide

Downstream raw materials:

1,3-bis(aminomethyl)-5-azidomethyl-2,4,6-triethylbenzene

C₃₇H₅₅N₇O₄

C₂₇H₃₅N₇O₂