(E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate

Base Information

• Chemical Name: (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate
• CAS No.: 172854-02-3
• Molecular Formula: C₁₁H₁₂BrNO₄
• Molecular Weight: 302.125
• Mol file: 172854-02-3.mol

Synonyms:(E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate

Chemical Property of (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate

There total 11 articles about (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C13H15BrO4 (1390630-45-1) → (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate (172854-02-3)

Guidance literature:

With n-Butyl nitrite; sodium ethanolate; In ethanol; at 0 ℃;

DOI:10.1016/j.tetlet.2012.05.149

Reference yield: 60.0%

ethyl 3-(4-hydroxyphenyl)-2-(hydroxyimino)propanoate → (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate (172854-02-3)

Guidance literature:

With N-bromoacetamide; In tetrahydrofuran; at -78.1 ℃;

DOI:10.1107/S0108270195007335

Reference yield:

C11H11BrO4 → (E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoate (172854-02-3)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In methanol; at 0 ℃; for 6.5h; Inert atmosphere;

DOI:10.1039/c0ob00824a

upstream raw materials:

tyrosine ethyl ester

L-tyrosine ethyl ester

ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate

ethyl 3-(3-bromo-4-hydroxyphenyl)-2,3-dihydroxypropanoate

Downstream raw materials:

psammaplin A

(E)-ethyl 3-(3-bromo-4-hydroxyphenyl)-2-{[(tetrahydro-2H-pyran-2-yl)oxy]imino}propanoate

2-(3-bromo-4-hydroxyphenyl)acetonitrile

(E)-3-(3-bromo-4-hydroxyphenyl)-2-(hydroxyimino)propanoic acid