Chemical Property of beta-ESCIN
Chemical Property:
- Appearance/Colour:white powder
- Vapor Pressure:0mmHg at 25°C
- Melting Point:222-223°
- Refractive Index:1.627
- Boiling Point:1140.642 °C at 760 mmHg
- Flash Point:311.842 °C
- PSA：0.00000
- Density:1.467 g/cm3
- LogP:1.02620
- Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
- XLogP3:0.7
- Hydrogen Bond Donor Count:13
- Hydrogen Bond Acceptor Count:24
- Rotatable Bond Count:16
- Exact Mass:1130.55090361
- Heavy Atom Count:79
- Complexity:2300
- Purity/Quality:
-
97% *data from raw suppliers
b-Aescin *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
22
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Biological Agents -> Plant Oils and Extracts
- Canonical SMILES:CC=C(C)C(=O)OC1C(C2(C(CC1(C)C)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CO)OC(=O)C
- Isomeric SMILES:C/C=C(/C)\C(=O)O[C@H]1[C@@H]([C@@]2([C@@H](C[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H]([C@]5(C)CO)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C)C)[C@@H]2CC1(C)C)C)O)CO)OC(=O)C
- Recent ClinicalTrials:Escin in Patients With Covid-19 Infection
- Recent EU Clinical Trials:A phase IIa, single-center, randomized, reference-controlled, observer-blind trial to assess the efficacy of a topical Aescin formulation in experimentally induced itch, wheal and flare reactions in patients with type-I allergy
-
Uses
Peripheral vascular disorders Escin has been used as a treatment for ischemic damage, hemorrhoids, and trauma or for recovery post-operation. Also used in the treatment of adenocarcinoma cell lines.
