Technology Process of tris(2-(N,N-dimethylcarbamoyloxy)phenyl)(isobutyl)silane
There total 2 articles about tris(2-(N,N-dimethylcarbamoyloxy)phenyl)(isobutyl)silane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
o-bromophenyl N,N-dimethylcarbamate;
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine;
In
tetrahydrofuran; hexane;
at -80 ℃;
for 1h;
Inert atmosphere;
isobutyltrichlorosilane;
In
tetrahydrofuran; hexane;
at -80 - 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1021/ol7030944
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / Inert atmosphere
2.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / Inert atmosphere
2.2: Inert atmosphere
With
N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; sodium hydride;
DOI:10.1002/chem.201002789
- Guidance literature:
-
tris(2-(N,N-dimethylcarbamoyloxy)phenyl)(isobutyl)silane;
With
lithium aluminium tetrahydride;
In
diethyl ether; dichloromethane;
at 20 ℃;
for 6h;
Inert atmosphere;
With
water;
In
dichloromethane;
Inert atmosphere;
DOI:10.1021/ol7030944
