2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Base Information

Chemical Name:2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside
CAS No.:890131-36-9
Molecular Formula:C₄₉H₄₆Cl₅NO₁₈
Molecular Weight:1114.17
Hs Code.:

2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Synonyms:2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Suppliers and Price of 2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

There total 10 articles about 2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: O-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosyluronate)-(1->3)-1,4,6-tri-O-acetyl-2-deoxy-2-trichloroacetamido-D-galactopyranose

: 890131-36-9
2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 10 steps

1: 89 percent / n-Bu₄NBr; BF₃*Et₂O; TMSBr / 2,4,6-collidine / CH₂Cl₂ / 48 h / 20 °C

2: 90 percent / trimethylsilyl trifluoromethanesulfonate / CH₂Cl₂ / 0.5 h

3: NaOMe / methanol

4: trifluoroacetic acid / 4 h

5: 83 percent / camphorsulfonic acid / dimethylformamide / 1.5 h

6: 92 percent / N,N-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH₂Cl₂ / 1 h

7: 79 percent / AcOH / CH₂Cl₂; H₂O / 24 h / 20 °C

8: 95 percent / pyridine / 1 h / 0 °C

9: AcOH / 0.5 h / 100 °C

10: pyridine / CH₂Cl₂ / 1 h / 0 °C

With pyridine; dmap; trimethylsilyl bromide; trimethylsilyl trifluoromethanesulfonate; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetrabutylammomium bromide; sodium methylate; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; 2,4,6-trimethyl-pyridine; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.200503551

Reference yield:

: 890131-32-5
O-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosyluronate)-(1->3)-2-trichloromethyl-(4,6-di-O-acetyl-1,2-dideoxy-α-D-galactopyrano)[2,1-d]2-oxazoline

: 890131-36-9
2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1: 90 percent / trimethylsilyl trifluoromethanesulfonate / CH₂Cl₂ / 0.5 h

2: NaOMe / methanol

3: trifluoroacetic acid / 4 h

4: 83 percent / camphorsulfonic acid / dimethylformamide / 1.5 h

5: 92 percent / N,N-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH₂Cl₂ / 1 h

6: 79 percent / AcOH / CH₂Cl₂; H₂O / 24 h / 20 °C

7: 95 percent / pyridine / 1 h / 0 °C

8: AcOH / 0.5 h / 100 °C

9: pyridine / CH₂Cl₂ / 1 h / 0 °C

With pyridine; dmap; trimethylsilyl trifluoromethanesulfonate; camphor-10-sulfonic acid; sodium methylate; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.200503551

Reference yield:

: (2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R,6R)-3-hydroxy-2-hydroxymethyl-6-(naphthalen-2-ylmethoxy)-5-(2,2,2-trichloro-acetylamino)-tetrahydro-pyran-4-yloxy]-tetrahydro-pyran-2-carboxylic acid methyl ester

: 890131-36-9
2-naphthylmethyl O-(methyl 2,3-di-O-benzoyl-4-O-levulinoyl-β-D-glucopyranosyluronate)-(1->3)-4,6-di-O-chloroacetyl-2-deoxy-2-trichloroacetamido-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: trifluoroacetic acid / 4 h

2: 83 percent / camphorsulfonic acid / dimethylformamide / 1.5 h

3: 92 percent / N,N-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH₂Cl₂ / 1 h

4: 79 percent / AcOH / CH₂Cl₂; H₂O / 24 h / 20 °C

5: 95 percent / pyridine / 1 h / 0 °C

6: AcOH / 0.5 h / 100 °C

7: pyridine / CH₂Cl₂ / 1 h / 0 °C

With pyridine; dmap; camphor-10-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.200503551