N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine

Base Information

• Chemical Name: N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine
• CAS No.: 111322-02-2
• Molecular Formula: C₂₄H₂₅N₅O₆
• Molecular Weight: 479.492
• Mol file: 111322-02-2.mol

Synonyms:N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine

Chemical Property of N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine

There total 1 articles about N⁶-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-6-benzoyl-2',3'-O-isopropylideneadenosine (39947-04-1) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → N6-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine (111322-02-2)

Guidance literature:

With pyridine; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1.) DMSO, 18 h, 2.) 1 h;

DOI:10.1021/jm00397a020

Reference yield: 82.0%

L-homocysteine disodium salt (50615-55-9) + N6-benzoyl-5'-deoxy-5'-(trans-carbethoxyvinyl)-2',3'-O-isopropylideneadenosine (111322-02-2) → N6-benzoyl-5'-deoxy-5'(RS)-L-homocystein-S-yl-5'-(carbethoxymethyl)-2',3'-O-isopropylideneadenosine

Guidance literature:

In tetrahydrofuran; for 0.5h;

DOI:10.1021/jm00397a020

upstream raw materials:

N-6-benzoyl-2',3'-O-isopropylideneadenosine

ethyl (triphenylphosphoranylidene)acetate