(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Base Information

Chemical Name:(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal
CAS No.:409319-63-7
Molecular Formula:C₃₉H₅₂O₈Si
Molecular Weight:676.923
Hs Code.:

Synonyms:(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Suppliers and Price of (2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

There total 4 articles about (2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 409319-73-9
(2S,3R,5R,6S)-2,6-bis(benzyloxy)-3-(t-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-4,4-dimethyl-1-oxiranylheptane-1,7-diol

: 409319-63-7
(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃;
DOI:10.1246/cl.2002.82

Reference yield:

: 182265-34-5
(2R,3R,5R,6S)-2,6-Dibenzyloxy-3,7-bis(tert-butyldimethylsiloxy)-5-(p-methoxybenzyloxy)-4,4-dimethylheptanal

: 409319-63-7
(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / tetrahydrofuran / 0 °C

2: 88 percent / aq. HCl / tetrahydrofuran / 20 °C

3: 96 percent / m-CPBA / CH₂Cl₂ / 50 °C

4: 95 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 0 °C

With hydrogenchloride; oxalyl dichloride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; 4: Swern oxidation;
DOI:10.1246/cl.2002.82

Reference yield:

: 409319-76-2
(2S,3R,5R,6S)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethylnon-8-ene-1,7-diol

: 409319-63-7
(2R,3R,5R,6R)-2,6-bis(benzyloxy)-5-(t-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-4,4-dimethyl-7-oxiranyl-7-oxapentanal

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / m-CPBA / CH₂Cl₂ / 50 °C

2: 95 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 0 °C

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 2: Swern oxidation;
DOI:10.1246/cl.2002.82