4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol

Base Information

• Chemical Name: 4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol
• CAS No.: 1169389-77-8
• Molecular Formula: C₂₆H₂₂N₄O₃
• Molecular Weight: 438.486

Synonyms:4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol

Chemical Property of 4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol

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Technology Process of 4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol

There total 1 articles about 4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

4-(5-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenyl acetate (1169389-76-7) → 4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol (1169389-77-8)

Guidance literature:

4-(5-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenyl acetate; With water; sodium hydroxide; In tetrahydrofuran; for 1h; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃;

Reference yield: 88.5%

4-(5-(4-(5-(4 tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenol (1169389-77-8) + bicyclo[2.2.1]hept-5-en-2-ylmethyl 4-methylbenzenesulfonate (50626-34-1,108266-85-9,108266-86-0) → 2-(4-(bicyclo[2.2.1]hept-5-en-2-ylmethoxy)phenyl)-5-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazole (1169389-78-9)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 - 100 ℃;

upstream raw materials:

4-(5-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)phenyl acetate

Downstream raw materials:

2-(4-(bicyclo[2.2.1]hept-5-en-2-ylmethoxy)phenyl)-5-(4-(5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl)phenyl)-1,3,4-oxadiazole

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