di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane

Base Information

• Chemical Name: di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane
• CAS No.: 554432-03-0
• Molecular Formula: C₃₂H₄₉OPSi
• Molecular Weight: 508.8
• Mol file: 554432-03-0.mol

Synonyms:di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane

Chemical Property of di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane

There total 4 articles about di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

t-butyldimethylsilyl-4-bromophenol (67963-68-2) + di-1-adamantylchlorophosphane (157282-19-4) → di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane (554432-03-0)

Guidance literature:

t-butyldimethylsilyl-4-bromophenol; With magnesium; In tetrahydrofuran;

With copper(I) bromide; In tetrahydrofuran; at 20 ℃; for 0.333333h;

di-1-adamantylchlorophosphane; In tetrahydrofuran; for 14h; Further stages.; Heating;

DOI:10.1002/chem.200390161

Reference yield:

4-bromo-phenol (106-41-2) → di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane (554432-03-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 98 percent / Et₃N / CH₂Cl₂ / 12 h / 20 °C

2.1: Mg / tetrahydrofuran

2.2: CuBr / tetrahydrofuran / 0.33 h / 20 °C

2.3: 63 percent / tetrahydrofuran / 14 h / Heating

With magnesium; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200390161

Reference yield:

di-1-adamantylphosphine (131211-27-3) → di-adamantan-1-yl-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-phosphane (554432-03-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 100 percent / CCl₄ / 16 h / 50 °C

2.1: Mg / tetrahydrofuran

2.2: CuBr / tetrahydrofuran / 0.33 h / 20 °C

2.3: 63 percent / tetrahydrofuran / 14 h / Heating

With tetrachloromethane; magnesium; In tetrahydrofuran;

DOI:10.1002/chem.200390161

upstream raw materials:

t-butyldimethylsilyl-4-bromophenol

di-1-adamantylchlorophosphane

4-bromo-phenol

di-1-adamantylphosphine