Sintamil

Base Information

Chemical Name:Sintamil
CAS No.:16398-39-3
Molecular Formula:C18H19 N3 O4 . Cl H
Molecular Weight:377.827
Hs Code.:
European Community (EC) Number:240-449-1
UNII:Y7LU3BJ31L
DSSTox Substance ID:DTXSID00936895
Wikidata:Q27294354
Mol file:16398-39-3.mol

Synonyms:10-(3-(dimethylamino)propyl)-2-nitrodibenz(b,f)(1,4)-oxazepin-11(10H)-one;233-Go;2330 Go;nitroxazepine;sintamil

Suppliers and Price of Sintamil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Sintamil

Chemical Property:

Vapor Pressure:1.09E-10mmHg at 25°C
Melting Point:227-229 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Boiling Point:514.3°Cat760mmHg
Flash Point:264.8°C
PSA：78.60000
Density:g/cm³
LogP:3.88720
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:377.1142338
Heavy Atom Count:26
Complexity:493

Purity/Quality:: 99%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=CC=CC=C2OC3=C(C1=O)C=C(C=C3)[N+](=O)[O-].Cl
Uses Nitroxazepine is an impurity of Amoxapine (A634230), which is an antidepressant.

Technology Process of Sintamil

There total 1 articles about Sintamil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16398-39-3
10-(3-dimethylamino-propyl)-2-nitro-10H-dibenzo[b,f][1,4]oxazepin-11-one; hydrochloride

Guidance literature:: Oxazepin I,Me2N-(CH2)3Cl*HCl II;

Reference yield:

: 16398-39-3
10-(3-dimethylamino-propyl)-2-nitro-10H-dibenzo[b,f][1,4]oxazepin-11-one; hydrochloride

: 54026-13-0
1-methyl-1-[3-(2-nitro-11-oxo-11H-dibenzo[b,f][1,4]oxazepin-10-yl)-propyl]-3-phenyl-urea

Guidance literature:: Multi-step reaction with 3 steps

1: xylene / 7 h / Heating

2: HBr / acetic acid

3: benzene

With hydrogen bromide; In acetic acid; xylene; benzene;

Reference yield:

: 16398-39-3
10-(3-dimethylamino-propyl)-2-nitro-10H-dibenzo[b,f][1,4]oxazepin-11-one; hydrochloride

: 54026-05-0
2-nitro-10-[3-(toluene-4-sulfonylamino)-propyl]-10H-dibenzo[b,f][1,4]oxazepin-11-one

Guidance literature:: Multi-step reaction with 2 steps

1: ClCO₂Et / xylene / 7 h / Heating

2: dimethylformamide / 16 h / 110 °C

With chloroformic acid ethyl ester; In N,N-dimethyl-formamide; xylene;