Technology Process of bis[4-tert-butyl-2,6-bis(isopropoxymethyl)phenyl] disulfide
There total 4 articles about bis[4-tert-butyl-2,6-bis(isopropoxymethyl)phenyl] disulfide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-bromo-5-tert-butyl-1,3-bis(isopropoxymethyl)benzene;
With
iodine; magnesium;
In
tetrahydrofuran;
for 2h;
Reflux;
Inert atmosphere;
With
sulfur;
In
tetrahydrofuran;
for 2h;
Cooling with ice;
Reflux;
Inert atmosphere;
With
potassium hexacyanoferrate(III);
In
tetrahydrofuran; water;
Cooling with ice;
DOI:10.1021/ja106343h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: bromine / 5.5 h / 130 °C / Inert atmosphere
1.2: 100 °C / Inert atmosphere
2.1: hydrogen bromide / water / 12 h / 120 °C
3.1: sodium / 100 °C / Inert atmosphere
3.2: 5 h / 90 - 100 °C / Inert atmosphere
4.1: iodine; magnesium / tetrahydrofuran / 2 h / Reflux; Inert atmosphere
4.2: 2 h / Cooling with ice; Reflux; Inert atmosphere
4.3: Cooling with ice
With
hydrogen bromide; bromine; iodine; sodium; magnesium;
In
tetrahydrofuran; water;
DOI:10.1021/ja106343h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium / 100 °C / Inert atmosphere
1.2: 5 h / 90 - 100 °C / Inert atmosphere
2.1: iodine; magnesium / tetrahydrofuran / 2 h / Reflux; Inert atmosphere
2.2: 2 h / Cooling with ice; Reflux; Inert atmosphere
2.3: Cooling with ice
With
iodine; sodium; magnesium;
In
tetrahydrofuran;
DOI:10.1021/ja106343h