4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde

Base Information

• Chemical Name: 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde
• CAS No.: 224966-54-5
• Molecular Formula: C₄₇H₆₆O₃
• Molecular Weight: 679.039
• Mol file: 224966-54-5.mol

Synonyms:4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde

Chemical Property of 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde

There total 16 articles about 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-[4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-phenyl]-5,5-dimethyl-[1,3]dioxane (224966-51-2) → 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde (224966-54-5)

Guidance literature:

With water; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1039/a900829b

Reference yield:

(E)-3,5-Bis(dodecyloxy)-N-phenylbenzaldimin (148172-15-0) → 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde (224966-54-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / t-BuOK / dimethylformamide / 1 h / 80 °C

2: 96 percent / aq. CF₃CO₂H / CH₂Cl₂ / 5 h / 20 °C

With potassium tert-butylate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; 1: Condensation / 2: Hydrolysis;

DOI:10.1021/ja9941072

Reference yield:

(E)-1-[4-(4,4-dimethyl-2,6-dioxan-1-yl)phenyl]-2-(4-methylphenyl)ethene (224966-39-6) → 4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzaldehyde (224966-54-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / t-BuOK / dimethylformamide / 1 h / 80 °C

2: 96 percent / aq. CF₃CO₂H / CH₂Cl₂ / 5 h / 20 °C

With potassium tert-butylate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; 1: Condensation / 2: Hydrolysis;

DOI:10.1021/ja9941072

upstream raw materials:

2-[4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-phenyl]-5,5-dimethyl-[1,3]dioxane

1-ethenyl-4-methylbenzene

5-(hydroxymethyl)benzene-1,3-diol

4-(5,5-dimethyl-1,3-dioxan-2-yl)benzaldehyde

Downstream raw materials:

4-[4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-benzyloxy]-benzoic acid methyl ester

1-((E)-2-{4-[(E)-2-(4-Chloromethyl-phenyl)-vinyl]-phenyl}-vinyl)-3,5-bis-dodecyloxy-benzene

4-{(E)-2-[4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-phenyl]-vinyl}-benzaldehyde

[4-((E)-2-{4-[(E)-2-(3,5-Bis-dodecyloxy-phenyl)-vinyl]-phenyl}-vinyl)-phenyl]-methanol