2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde

Base Information

Chemical Name:2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde
CAS No.:1356935-74-4
Molecular Formula:C₁₉H₁₆F₃NO₃
Molecular Weight:363.336
Hs Code.:

Synonyms:2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde

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Technology Process of 2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde

There total 1 articles about 2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 102-96-5
(2-nitroethenyl)benzene

: 1356935-78-8
(E)-3-(4-(trifluoromethyl)phenyl)acrylaldehyde

: 1356935-74-4
2-((1R,2S,3R,4R)-2-nitro-3-phenyl-4-(4-(trifluoromethyl)phenyl)cyclobutyl)acetaldehyde

Guidance literature:: With diethylacetamide; (S)-3-(3,5-bis(trifluoromethyl)phenylamino)-4-(pyrrolidin-2-ylmethylamino)cyclobut-3-ene-1,2-dione; water; In dichloromethane; at 20 ℃; for 22h; optical yield given as %ee; stereoselective reaction;
DOI:10.1021/ja211878x