Technology Process of C24H37NO5Si
There total 4 articles about C24H37NO5Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(S)-4-benzyl-3-propionyl-2-oxazolidinone;
With
titanium tetrachloride;
In
dichloromethane;
at 0 ℃;
for 0.0833333h;
With
(-)-sparteine;
In
dichloromethane;
at 0 ℃;
for 0.333333h;
(R)-3-((tert-butyldimethylsilyl)oxy)pent-4-enal;
In
dichloromethane;
at -78 - 0 ℃;
for 2h;
DOI:10.1021/ol401357k
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: triethylamine; tetrabutyl ammonium fluoride / dichloromethane / 1 h / 0 °C
2.1: pyridinium p-toluenesulfonate / methanol; dichloromethane / 20 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C
3.2: 1 h / -78 °C
4.1: titanium tetrachloride / dichloromethane / 0.08 h / 0 °C
4.2: 0.33 h / 0 °C
4.3: 2 h / -78 - 0 °C
With
oxalyl dichloride; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; titanium tetrachloride; dimethyl sulfoxide; triethylamine;
In
methanol; dichloromethane;
3.1: |Swern Oxidation / 3.2: |Swern Oxidation;
DOI:10.1021/ol401357k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridinium p-toluenesulfonate / methanol; dichloromethane / 20 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C
2.2: 1 h / -78 °C
3.1: titanium tetrachloride / dichloromethane / 0.08 h / 0 °C
3.2: 0.33 h / 0 °C
3.3: 2 h / -78 - 0 °C
With
oxalyl dichloride; pyridinium p-toluenesulfonate; titanium tetrachloride; dimethyl sulfoxide;
In
methanol; dichloromethane;
2.1: |Swern Oxidation / 2.2: |Swern Oxidation;
DOI:10.1021/ol401357k
