Benzoic acid, 5-(phenylmethoxy)-2-[[4-(phenylmethoxy)-3-(trifluoromethyl)phenyl]amino]-

Base Information

• Chemical Name: Benzoic acid, 5-(phenylmethoxy)-2-[[4-(phenylmethoxy)-3-(trifluoromethyl)phenyl]amino]-
• CAS No.: 82578-53-8
• Molecular Formula: C₂₈H₂₂F₃NO₄
• Molecular Weight: 493.482
• Mol file: 82578-53-8.mol

Synonyms:5-Benzyloxy-N-(4-benzyloxy-3-trifluormethylphenyl)anthranilsaeure

Chemical Property of Benzoic acid, 5-(phenylmethoxy)-2-[[4-(phenylmethoxy)-3-(trifluoromethyl)phenyl]amino]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 5-(phenylmethoxy)-2-[[4-(phenylmethoxy)-3-(trifluoromethyl)phenyl]amino]-

There total 7 articles about Benzoic acid, 5-(phenylmethoxy)-2-[[4-(phenylmethoxy)-3-(trifluoromethyl)phenyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.4%

5-(benzyloxy)-2-chlorobenzoic acid (39062-64-1) + 3-(trifluoromethyl)-4-(benzyloxy)aniline (70338-47-5) → 5-Benzyloxy-N-(4-benzyloxy-3-trifluormethylphenyl)anthranilsaeure (82578-53-8)

Guidance literature:

With potassium carbonate; copper; at 160 ℃; for 2h;

Reference yield:

2-chloro-5-nitrobenzoic acid (2516-96-3) → 5-Benzyloxy-N-(4-benzyloxy-3-trifluormethylphenyl)anthranilsaeure (82578-53-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 97 percent / H₂ / Pt

2: 1) NaNO₂

3: 87 percent / NaOH

4: 73.4 percent / K₂CO₃ / Cu powder / 2 h / 160 °C

With sodium hydroxide; hydrogen; potassium carbonate; sodium nitrite; copper; platinum;

Reference yield:

4-benzyloxy-3-trifluoromethyl-nitrobenzene (39062-69-6) → 5-Benzyloxy-N-(4-benzyloxy-3-trifluormethylphenyl)anthranilsaeure (82578-53-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 98.8 percent / H₂ / Pt

2: 73.4 percent / K₂CO₃ / Cu powder / 2 h / 160 °C

With hydrogen; potassium carbonate; copper; platinum;

upstream raw materials:

5-(benzyloxy)-2-chlorobenzoic acid

3-(trifluoromethyl)-4-(benzyloxy)aniline

2-chloro-5-nitrobenzoic acid

4-benzyloxy-3-trifluoromethyl-nitrobenzene

Downstream raw materials:

5,4'-Dihydroxyflufenaminsaeure