Technology Process of 3-(2-benzyloxyethyl)-2,5-dimethoxy-4-methyl-2-vinylbenzaldehyde
There total 11 articles about 3-(2-benzyloxyethyl)-2,5-dimethoxy-4-methyl-2-vinylbenzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide;
tetrakis(triphenylphosphine) palladium(0);
In
toluene;
for 40h;
Heating;
DOI:10.1039/b205487f
- Guidance literature:
-
Multi-step reaction with 11 steps
1: 79 percent / sodium hydride / dimethylformamide / 7 h
2: 66 percent / decahydronaphthalene / 7 h / Heating
3: 83 percent / PhI(OAc)2
4: 70 percent / zinc; acetic acid / 7 h
5: 92 percent / K2CO3 / dimethylformamide
6: 97 percent / TsOH*H2O / methanol / Heating
7: 95 percent / OsO4; NaIO4 / CCl4; H2O; 2-methyl-propan-2-ol / 1.5 h
8: 95 percent / NaBH4 / methanol / 1.5 h / 0 °C
9: 92 percent / sodium hydride / tetrahydrofuran; various solvent(s) / 0 °C
10: 95 percent / Amberlite IR 120 / acetone; H2O
11: 66 percent / Pd(PPh3)4; CuI / toluene / 40 h / Heating
With
sodium tetrahydroborate; sodium periodate; copper(l) iodide; osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium(0); [bis(acetoxy)iodo]benzene; Amberlite IR 120; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; zinc;
In
tetrahydrofuran; methanol; tetrachloromethane; water; N,N-dimethyl-formamide; acetone; toluene; decalin; tert-butyl alcohol;
2: Claisen rearrangement / 11: Stille coupling;
DOI:10.1021/jo040115b
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 66 percent / decahydronaphthalene / 7 h / Heating
2: 83 percent / PhI(OAc)2
3: 70 percent / zinc; acetic acid / 7 h
4: 92 percent / K2CO3 / dimethylformamide
5: 97 percent / TsOH*H2O / methanol / Heating
6: 95 percent / OsO4; NaIO4 / CCl4; H2O; 2-methyl-propan-2-ol / 1.5 h
7: 95 percent / NaBH4 / methanol / 1.5 h / 0 °C
8: 92 percent / sodium hydride / tetrahydrofuran; various solvent(s) / 0 °C
9: 95 percent / Amberlite IR 120 / acetone; H2O
10: 66 percent / Pd(PPh3)4; CuI / toluene / 40 h / Heating
With
sodium tetrahydroborate; sodium periodate; copper(l) iodide; osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium(0); [bis(acetoxy)iodo]benzene; Amberlite IR 120; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; zinc;
In
tetrahydrofuran; methanol; tetrachloromethane; water; N,N-dimethyl-formamide; acetone; toluene; decalin; tert-butyl alcohol;
1: Claisen rearrangement / 10: Stille coupling;
DOI:10.1021/jo040115b
