Eniluracil

Base Information

Chemical Name:Eniluracil
CAS No.:59989-18-3
Molecular Formula:C6H4N2O2
Molecular Weight:136.11
Hs Code.:
NSC Number:687296
UNII:2E2W0W5XIU
DSSTox Substance ID:DTXSID10208696
Nikkaji Number:J574.717A
Wikidata:Q27094456
NCI Thesaurus Code:C1773
Pharos Ligand ID:6P943SJ7TB4M
Metabolomics Workbench ID:148030
ChEMBL ID:CHEMBL355200
Mol file:59989-18-3.mol

Synonyms:5-ethynyluracil;776C85;compound 776C;eniluracil;GW776C85

Suppliers and Price of Eniluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Eniluracil
1g
$ 495.00

TRC
Eniluracil
10mg
$ 55.00

TCI Chemical
5-Ethynyluracil >97.0%(HPLC)(T)
200mg
$ 189.00

TCI Chemical
5-Ethynyluracil >97.0%(HPLC)(T)
1g
$ 656.00

Crysdot
5-Ethynylpyrimidine-2,4(1H,3H)-dione 95+%
10g
$ 1188.00

Crysdot
5-Ethynylpyrimidine-2,4(1H,3H)-dione 95+%
1g
$ 347.00

Crysdot
5-Ethynylpyrimidine-2,4(1H,3H)-dione 95+%
5g
$ 742.00

Chemenu
5-Ethynylpyrimidine-2,4(1H,3H)-dione 95%
1g
$ 475.00

American Custom Chemicals Corporation
ENILURACIL 95.00%
100MG
$ 779.63

American Custom Chemicals Corporation
ENILURACIL 95.00%
1G
$ 1229.55

Total 22 raw suppliers

Chemical Property of Eniluracil

Chemical Property:

Melting Point:320° (dec)
Refractive Index:1.589
PKA:7.44±0.10(Predicted)
PSA：65.72000
Density:1.39 g/cm³
LogP:-0.95550
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Soluble in DMSO
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:136.027277375
Heavy Atom Count:10
Complexity:269

Purity/Quality:

99%, ^*data from raw suppliers

Eniluracil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=CNC(=O)NC1=O
Recent ClinicalTrials:Eniluracil Hand Foot Syndrome
Description Eniluracil (59989-18-3) is an irreversible dihydropyrimidine dehydrogenase (DPD) inhibitor.1-3? DPD is involved in the degradation of pyrimidine-based chemotherapeutic drugs such as 5-fluorouracil (5-FU).? Eniluracil has been used along with 5-FU to prolong circulating concentrations of the drug.
Uses Potent inactivator of Dihydropyrimidine dehydrogenase (DPD).

Technology Process of Eniluracil

There total 10 articles about Eniluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 83355-90-2
5-(trimethylsilylethynyl)uracil

: 59989-18-3
5-ethynyluracil

Guidance literature:: 5-(trimethylsilylethynyl)uracil; With pyrographite; sodium hydroxide; In water; Large scale;

With acetic acid; In water; pH=5; Large scale;
DOI:10.1021/op0100100