ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate

Base Information

• Chemical Name: ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate
• CAS No.: 1431225-12-5
• Molecular Formula: C₂₃H₂₄N₂O₅
• Molecular Weight: 408.454
• Mol file: 1431225-12-5.mol

Synonyms:ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate

Chemical Property of ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate

Chemical Property:

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Technology Process of ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate

There total 1 articles about ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1,5-dimethyl-1H-indole (27816-53-1) + C13H13NO5 → ethyl 2-(4-(1, 5-dimethyl-1H-indol-3-yl)-3-nitrochroman-2-yl)acetate (1431225-12-5)

Guidance literature:

With C₄₂H₃₃N₃O₂; zinc trifluoromethanesulfonate; In toluene; at 20 ℃; for 24h; enantioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1055/s-0032-1318200

upstream raw materials:

1,5-dimethyl-1H-indole