Technology Process of (±)-latifolin
There total 6 articles about (±)-latifolin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
quinoline; 5% palladium on barium sulphate; hydrogen;
In
ethyl acetate;
at 20 ℃;
for 12h;
under 760.051 Torr;
DOI:10.1002/cjoc.201500505
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C
1.2: 2 h / 0 °C
2.1: n-butyllithium / hexane; tetrahydrofuran / 1.33 h / -78 - 20 °C
2.2: 1 h / -78 - 20 °C
3.1: iodine / acetonitrile / 0.5 h / -10 - 20 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C
5.1: 5% palladium on barium sulphate; quinoline; hydrogen / ethyl acetate / 12 h / 20 °C / 760.05 Torr
With
quinoline; n-butyllithium; 5% palladium on barium sulphate; tetrabutyl ammonium fluoride; hydrogen; iodine; sodium hydride;
In
tetrahydrofuran; hexane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/cjoc.201500505
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iodine / acetonitrile / 0.5 h / -10 - 20 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C
3: 5% palladium on barium sulphate; quinoline; hydrogen / ethyl acetate / 12 h / 20 °C / 760.05 Torr
With
quinoline; 5% palladium on barium sulphate; tetrabutyl ammonium fluoride; hydrogen; iodine;
In
tetrahydrofuran; ethyl acetate; acetonitrile;
DOI:10.1002/cjoc.201500505
