3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester

Base Information

• Chemical Name: 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester
• CAS No.: 499765-80-9
• Molecular Formula: C₃₄H₃₆N₂O₈
• Molecular Weight: 600.668

Synonyms:3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester

Chemical Property of 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester

There total 5 articles about 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.9%

5-iodo-4-(2-methoxycarbonyl-ethyl)-3-methyl-pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-tert-butyl ester (850425-82-0) → 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester (499765-80-9)

Guidance literature:

With copper; In toluene; at 120 ℃; for 40h;

DOI:10.1039/b718627d

Reference yield:

Benzyl 5-Iodo-4-(2-methoxycarbonylethyl)-3-methylpyrrole-2-carboxylate (31896-87-4) → 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester (499765-80-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 4-N,N'-dimethylaminopyridine / CH₂Cl₂ / 0.5 h / 20 °C

2: Cu / dimethylformamide / 1 h / 100 °C

3: 2.9 g / 0.5 h / 170 °C

With dmap; copper; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja0265052

Reference yield:

3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-[2,2']bipyrrolyl-1,5,1',5'-tetracarboxylic acid 5,5'-dibenzyl ester 1,1'-di-tert-butyl ester → 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester (499765-80-9)

Guidance literature:

at 170 ℃; for 0.5h;

DOI:10.1021/ja0265052

upstream raw materials:

5-iodo-4-(2-methoxycarbonyl-ethyl)-3-methyl-pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-tert-butyl ester

Benzyl 5-Iodo-4-(2-methoxycarbonylethyl)-3-methylpyrrole-2-carboxylate

benzyl 4-(2-methoxycarbonylethyl)-3,5-dimethylpyrrole-2-carboxylate

5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-methylpyrrole-2-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 499765-80-9 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send