N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

Base Information

Chemical Name:N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide
CAS No.:111773-28-5
Molecular Formula:C₁₅H₁₈Br₂FNO₃
Molecular Weight:439.119
Hs Code.:

Synonyms:N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

Suppliers and Price of N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

There total 1 articles about N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 111773-26-3
2,3-dibromo-2-fluoropropanoyl chloride

: 111773-25-2
tert-butyl 3-amino-4-methylbenzoate

: 111773-28-5
N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

Guidance literature:: With 2,3-Lutidine; In toluene; at 20 ℃; for 0.5h;
DOI:10.1021/jm00397a018

Reference yield: 78.0%

: 111773-28-5
N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

: 111773-32-1
N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-3-bromo-3-fluoroazetidin-2-one

Guidance literature:: With sodium hydride; In dichloromethane; N,N-dimethyl-formamide; for 2h;
DOI:10.1021/jm00397a018

Reference yield:

: 111773-28-5
N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,3-dibromo-2-fluoropropanoic acid amide

: 111773-39-8
N-(3-carboxy-6-methylphenyl)-3-fluoroazetidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / NaH / dimethylformamide; CH₂Cl₂ / 2 h

2: 99 percent / nBu₃SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 1.5 h / 60 °C

3: 90 percent / CF₃CO₂H / CH₂Cl₂ / 1 h / 10 °C

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00397a018