(R)-N,alpha-dimethylphenethylamine hydrochloride

Base Information

• Chemical Name: (R)-N,alpha-dimethylphenethylamine hydrochloride
• CAS No.: 826-10-8
• Molecular Formula: C10H15N•ClH
• Molecular Weight: 185.697
• Mol file: 826-10-8.mol

Synonyms:Einecs 212-552-1;Benzeneethanamine,N,a-dimethyl-,hydrochloride,(aR)-(9CI);L-Methamphetamine HCl;(R)-2-N-methylamino-1-phenylpropane hydrochloride;(-)methamphetamine HCl;(-)-methamphetamine hydrochloride;Benzeneethanamine,N,a-dimethyl-,hydrochloride,(R);l-Methamphetamine hydrochloride;Methamphtamine hydrochloride;(R)-(-)-methamphetamine hydrochloride;(R)-(-)-methamphetamine HCl;L-Desoxyephedrine hydrochloride;

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of (R)-N,alpha-dimethylphenethylamine hydrochloride

Chemical Property:

• Melting Point: 172-174°C
• PSA: 12.03000
• LogP: 3.02990
• Storage Temp.: Controlled Substance, -20°C Freezer

Purity/Quality:

Safty Information:

• Hazard Codes: T
• Statements: 63-23/24/25
• Safety Statements: 22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Description: (?)-Methamphetamine (hydrochloride) (Item No. 13998) is an analytical reference material categorized as an amphetamine. It is the less physiologically active isomer of (±)-methamphetamine ( | 14216). (?)-Methamphetamine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Technology Process of (R)-N,alpha-dimethylphenethylamine hydrochloride

There total 1 articles about (R)-N,alpha-dimethylphenethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-(-)-deprenyl hydrochloride (14611-52-0,2079-54-1) → (R)-2-N-methylamino-1-phenylpropane hydrochloride (826-10-8,4298-16-2)

Guidance literature:

With phosphate buffer; at 105 ℃; Thermodynamic data; Rate constant; Kinetics; ΔE(excit.); other reagent; other temperature;

DOI:10.1002/jps.2600830913

Reference yield: 97.0%

(R)-2-N-methylamino-1-phenylpropane hydrochloride (826-10-8,4298-16-2) + 1,1'-carbonyldiimidazole (530-62-1) → (R)-N-Methyl-N-(1-phenylpropan-2-yl)-1H-imidazole-1-carboxamide (1247027-65-1)

Guidance literature:

With pyridine; In water; ethyl acetate; at 12 - 90 ℃; Inert atmosphere;

Reference yield: 85.0%

(R)-2-N-methylamino-1-phenylpropane hydrochloride (826-10-8,4298-16-2) + propargyl bromide (106-96-7) → SELEGILINE (2323-36-6,4528-51-2,4530-70-5,14611-51-9)

Guidance literature:

With potassium carbonate; In toluene; acetonitrile; at 20 ℃; for 3h; enantioselective reaction;

DOI:10.1016/j.tetlet.2015.10.010

upstream raw materials:

(R)-(-)-deprenyl hydrochloride

Downstream raw materials:

(R)-N-Methyl-N-(1-phenylpropan-2-yl)-1H-imidazole-1-carboxamide

SELEGILINE

Refernces