methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

Base Information

Chemical Name:methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate
CAS No.:1351956-77-8
Molecular Formula:C₂₄H₂₇N₅O₂S
Molecular Weight:449.577
Hs Code.:

Synonyms:methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

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Chemical Property of methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

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Technology Process of methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

There total 10 articles about methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1351956-64-3
1-(2-bromobenzo[d]thiazol-6-yl)-1-(1H-imidazol-1-yl)-N,N-dimethylbutan-2-amine

: 619-45-4
4-methoxycarbonyl aniline

: 1351956-77-8
methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

Guidance literature:: With hydrogenchloride; In 1,2-dichloro-ethane; butan-1-ol; Reflux;

Reference yield:

: methyl 3-(((6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]-thiazol-2-yl)amino)methyl)benzoate

: 1351956-77-8
methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) bromide; sodium nitrite; hydrogen bromide / water / 3 h / -10 - -5 °C

2: hydrogenchloride / butan-1-ol; 1,2-dichloro-ethane / Reflux

With hydrogenchloride; hydrogen bromide; copper(ll) bromide; sodium nitrite; In water; 1,2-dichloro-ethane; butan-1-ol;

Reference yield:

: 1351956-54-1
6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-amine

: 1351956-77-8
methyl 4-((6-(-2-(dimethylamino)-1-(1H-imidazol-1-yl)butyl)benzo[d]thiazol-2-yl)amino)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogen bromide; sodium nitrite / water / 0.42 h / -10 - 0 °C

1.2: 3 h / -10 °C

2.1: hydrogenchloride / water; 1,2-dichloro-ethane; butan-1-ol / Reflux

With hydrogenchloride; hydrogen bromide; sodium nitrite; In water; 1,2-dichloro-ethane; butan-1-ol;