(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Base Information

Chemical Name:(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene
CAS No.:1609460-96-9
Molecular Formula:C₆₁H₈₆N₂O₈
Molecular Weight:975.362
Hs Code.:

Synonyms:(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Suppliers and Price of (2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

There total 12 articles about (2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1609460-95-8
(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzyl)-1,5-anhydro-D-galacto-2-nonadecene

: 1609460-96-9
(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Guidance literature:: With ammonium formate; sodium cyanoborohydride; In methanol; at 20 ℃; Inert atmosphere;
DOI:10.1021/jo500769f

Reference yield:

: 1609460-81-2
dimethyl [(3,4,5,7-tetra-O-benzyl-6-O-p-methoxybenzyloxy-D-galacto)-1-oxomethyl]phosphonate

: 1609460-96-9
(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / ethanol / 1 h / 20 °C / Inert atmosphere

2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 5 h / 0 - 20 °C / Inert atmosphere

3: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

4: ammonium formate; sodium cyanoborohydride / methanol / 20 °C / Inert atmosphere

With ammonium formate; sodium cyanoborohydride; sodium hydrogencarbonate; potassium carbonate; Dess-Martin periodane; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; ethanol; dichloromethane; water; 1: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/jo500769f

Reference yield:

: 799267-98-4
1-N-tert-butyloxycarbonyl-3,4-O-isopropylidene-phytosphingosine

: 1609460-96-9
(2E,3S,4S,5R)-3-[N-(tert-butoxycarbonyl)amino]-4,5-O-isopropylidene-(2,3,4,6-tetra-O-benzylaza-β-D-galactopyranosyl)-2-nonadecene

Guidance literature:: Multi-step reaction with 5 steps

1: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

2: potassium carbonate / ethanol / 1 h / 20 °C / Inert atmosphere

3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 5 h / 0 - 20 °C / Inert atmosphere

4: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

5: ammonium formate; sodium cyanoborohydride / methanol / 20 °C / Inert atmosphere

With ammonium formate; sodium cyanoborohydride; sodium hydrogencarbonate; potassium carbonate; Dess-Martin periodane; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; ethanol; dichloromethane; water; 2: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/jo500769f