(5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester

Base Information

• Chemical Name: (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester
• CAS No.: 149194-47-8
• Molecular Formula: C₂₅H₂₉N₂O₅P
• Molecular Weight: 468.489
• Mol file: 149194-47-8.mol

Synonyms:(5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester

Chemical Property of (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester

There total 7 articles about (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenyl benzyloxycarbonylamino-(4-phthalimidobutyl)methanephosphonate (149194-44-5) → (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester (149194-47-8)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)73578-7

Reference yield:

O-benzyl carbamate (621-84-1) → (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester (149194-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 150 °C / microwave irradiation

2: hydrazine

With hydrazine; In acetic acid;

DOI:10.1016/j.bmcl.2006.03.012

Reference yield:

5-phthalimido-1-pentanal (95691-09-1) → (5-Amino-1-benzyloxycarbonylamino-pentyl)-phosphonic acid diphenyl ester (149194-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 150 °C / microwave irradiation

2: hydrazine

With hydrazine; In acetic acid;

DOI:10.1016/j.bmcl.2006.03.012

upstream raw materials:

diphenyl benzyloxycarbonylamino-(4-phthalimidobutyl)methanephosphonate

triphenyl phosphite

O-benzyl carbamate

5-phthalimido-1-pentanal

Downstream raw materials:

C₂₆H₃₁N₄O₅P

diphenyl ((N-benzyloxycarbonyl-O-tert-butyl-D-seryl)-L-alanyl)amino-(4-(N,N'-bis(tert-butyloxycarbonyl)guanyl)butyl)methanephosphonate

diphenyl (N-benzyloxycarbonyl-L-alanyl)amino-(4-(N,N'-bis(tert-butyloxycarbonyl)guanyl)butyl)methanephosphonate