C₃₂H₄₂O₃

Base Information

• Chemical Name: C₃₂H₄₂O₃
• CAS No.: 1318052-24-2
• Molecular Formula: C₃₂H₄₂O₃
• Molecular Weight: 474.684
• Mol file: 1318052-24-2.mol

Synonyms:C₃₂H₄₂O₃

Chemical Property of C₃₂H₄₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₄₂O₃

There total 12 articles about C₃₂H₄₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C34H46O5 (1186505-19-0) → C32H42O3 (1318052-24-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 1h; Reflux;

DOI:10.1016/j.tet.2011.05.092

Reference yield:

C20H34O (1318052-00-4) → C32H42O3 (1318052-24-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h / -60 °C / Inert atmosphere

1.2: 0.17 h / -60 °C / Inert atmosphere

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 °C

3.1: pyrrolidine / diethyl ether / 20 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / 0 °C / Inert atmosphere

4.2: 8 h / 0 - 20 °C / Inert atmosphere

5.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 - 20 °C / Inert atmosphere

5.2: 0 - 35 °C / Inert atmosphere

6.1: 24 h / 110 °C / Inert atmosphere

7.1: lithium aluminium tetrahydride / diethyl ether / 1 h / 0 °C / Reflux

With pyrrolidine; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; sodium hydride; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 1.1: Swern oxidation / 1.2: Swern oxidation / 4.2: Wittig reaction / 6.1: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.05.092

Reference yield:

C21H34O2 (1318051-97-6) → C32H42O3 (1318052-24-2)

Guidance literature:

Multi-step reaction with 8 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 6 h / 0 °C

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h / -60 °C / Inert atmosphere

2.2: 0.17 h / -60 °C / Inert atmosphere

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 °C

4.1: pyrrolidine / diethyl ether / 20 °C

5.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / 0 °C / Inert atmosphere

5.2: 8 h / 0 - 20 °C / Inert atmosphere

6.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 - 20 °C / Inert atmosphere

6.2: 0 - 35 °C / Inert atmosphere

7.1: 24 h / 110 °C / Inert atmosphere

8.1: lithium aluminium tetrahydride / diethyl ether / 1 h / 0 °C / Reflux

With pyrrolidine; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; sodium hydride; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 2.1: Swern oxidation / 2.2: Swern oxidation / 5.2: Wittig reaction / 7.1: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.05.092

upstream raw materials:

C₂₁H₃₄O

C₂₁H₃₂O

C₂₁H₃₄O

C₂₈H₄₀O