3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine

Base Information

• Chemical Name: 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine
• CAS No.: 97776-92-6
• Molecular Formula: C₃₉H₃₆N₆O₈
• Molecular Weight: 716.75

Synonyms:3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine

Chemical Property of 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine

There total 2 articles about 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (112237-60-2) + mono-4-methoxytrityl chloride (14470-28-1) → 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine (97776-92-6)

Guidance literature:

In pyridine; for 18h; Ambient temperature;

DOI:10.1002/hlca.19870700808

Reference yield:

cordycepin (73-03-0) → 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine (97776-92-6)

Guidance literature:

Multi-step reaction with 3 steps

1: (NH₄)2SO₄ / dioxane / 3 h / Heating

2: 94 percent / CH₂Cl₂ / 18 h / Ambient temperature

3: 90 percent / pyridine / 18 h / Ambient temperature

With ammonium sulfate; In 1,4-dioxane; pyridine; dichloromethane;

DOI:10.1002/hlca.19870700808

Reference yield: 96.0%

3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine (97776-92-6) + 2-dansylethyl chloroformate hydrochloride → Carbonic acid 2-(5-dimethylamino-naphthalene-1-sulfonyl)-ethyl ester (2R,3R,5S)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-2-{6-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-purin-9-yl}-tetrahydro-furan-3-yl ester

Guidance literature:

With 1-methyl-1H-imidazole; 4 A molecular sieve; In dichloromethane; at 4 ℃; for 18h;

DOI:10.1002/hlca.19960790305

upstream raw materials:

3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

mono-4-methoxytrityl chloride

cordycepin

Downstream raw materials:

3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<2-(4-nitrophenyl)ethyl diisopropylphosphoramidite>

2'-O-<<2-(cholest-5-en-3β-yloxycarbonyl)ethyl>carbonyl>-3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)etoxycarbonyl>adenosine

2'-O-(cholest-5-en-3β-yloxycarbonyl)-3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

2'-O-<(tert-butyl)dimethylsilyl>-3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 97776-92-6 3'-deoxy-5'-O-monomethoxytrityl-6-N-[2-(4-nitrophenyl)-ethoxycarbonyl]-adenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send