ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate

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Chemical Name:ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate
CAS No.:1353741-21-5
Molecular Formula:C₂₀H₁₈N₂O₃S
Molecular Weight:366.441
Hs Code.:

Synonyms:ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate

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Technology Process of ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate

There total 1 articles about ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 141-97-9
ethyl acetoacetate

: 90-02-8
salicylaldehyde

: 1353741-21-5
ethyl 2-methyl-4-(2-hydroxy phenyl)-4H-pyrimido[2,1-b][1,3]benzothiazole-3-carboxylate

Guidance literature:: With aluminum (III) chloride; In neat (no solvent); at 60 - 70 ℃; for 2h; Green chemistry;
DOI:10.1007/s00044-011-9908-6