Chemical Property of Venturicidin B
Chemical Property:
- Vapor Pressure:1.98E-31mmHg at 25°C
- Melting Point:168-170°; mp 145-149° (ethyl acetate-petr ether)
- Boiling Point:823.4°C at 760 mmHg
- PKA:11.80±0.70(Predicted)
- Flash Point:240.9°C
- Density:1.14g/cm3
- XLogP3:5
- Hydrogen Bond Donor Count:4
- Hydrogen Bond Acceptor Count:10
- Rotatable Bond Count:9
- Exact Mass:706.46559830
- Heavy Atom Count:50
- Complexity:1200
- Purity/Quality:
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98%Min *data from raw suppliers
VenturicidinB *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCC(=O)C(C)C(C(C)CC(C)C1C(CC(C=CC(CCCC=C(C2C(=CCC(O2)(CC(=O)O1)O)C)C)OC3CC(C(C(O3)C)O)O)C)C)O
- Isomeric SMILES:CCC(=O)[C@@H](C)[C@H]([C@H](C)C[C@@H](C)[C@@H]1[C@@H](C[C@H](/C=C/[C@@H](CCC/C=C(/[C@@H]2C(=CC[C@@](O2)(CC(=O)O1)O)C)\C)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)O)O)C)C)O
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Description
Venturicidin B is a macrolide bacterial metabolite that has been found in Streptomyces.
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Uses
The macrolide antibiotic Venturicidin B, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Venturicidin A was originally isolated as an antifungal agent. Venturicidin B is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector.
