C₂₉H₄₀O₅S

Base Information

• Chemical Name: C₂₉H₄₀O₅S
• CAS No.: 952496-39-8
• Molecular Formula: C₂₉H₄₀O₅S
• Molecular Weight: 500.7
• Mol file: 952496-39-8.mol

Synonyms:C₂₉H₄₀O₅S

Chemical Property of C₂₉H₄₀O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₄₀O₅S

There total 23 articles about C₂₉H₄₀O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C23H35IO3 (919608-40-5) + sodium benzenesulfonate (873-55-2) → C29H40O5S (952496-39-8)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 6h;

DOI:10.1016/j.tet.2007.07.005

Reference yield:

methanesulfonic acid 5-(1-methyl-2-oxo-ethyl)-tetrahydro-furan-2-ylmethyl ester (919608-15-4) → C29H40O5S (952496-39-8)

Guidance literature:

Multi-step reaction with 14 steps

1.1: TiCl₄ / CH₂Cl₂ / 0.25 h / -78 °C

1.2: 95 percent / CH₂Cl₂ / 0.5 h / -78 °C

2.1: 66 percent / lithium aluminum hydride / diethyl ether / 0 - 20 °C

3.1: 90 percent / sodium hexamethyldisilazide / tetrahydrofuran; dimethylformamide / 0 - 20 °C

4.1: O₃ / CH₂Cl₂ / 0.17 h / -78 °C

4.2: 97 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

5.1: 97 percent / magnesium bromide etherate / CH₂Cl₂ / 1 h / 20 °C

6.1: O₃ / CH₂Cl₂ / 0.25 h / -78 °C

6.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

7.1: 851 mg / sodium borohydride / methanol / 0 - 20 °C

8.1: 92 percent / TEA / CH₂Cl₂ / 14 h / 0 °C

9.1: 89 percent / PPTS / benzene / 2 h / Heating

10.1: 90 percent / NaI / acetone / 2 h / Heating

11.1: 91 percent / n-Bu₃SnH; Et₃B; air / toluene; hexane / -78 °C

12.1: 100 percent / lithium borohydride / diethyl ether; tetrahydrofuran / 0 - 20 °C

13.1: 99 percent / I₂; triphenylphosphine; imidazole / tetrahydrofuran / 0 - 20 °C

14.1: 91 percent / dimethylformamide / 6 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; lithium borohydride; air; triethyl borane; TEA; iodine; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; titanium tetrachloride; ozone; magnesium bromide ethyl etherate; triphenylphosphine; sodium iodide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; benzene;

DOI:10.1016/j.tet.2007.07.005

Reference yield:

5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-pentane-1,3-diol (919608-47-2) → C29H40O5S (952496-39-8)

Guidance literature:

Multi-step reaction with 21 steps

1.1: 3.59 g / imidazole / CH₂Cl₂ / 1 h / 20 °C

2.1: 98 percent / TEA / CH₂Cl₂ / 0 - 20 °C

3.1: 84 percent / CSA; methanol / 2 h / 20 °C

4.1: 80 percent / sodium hexamethyldisilazide / tetrahydrofuran / 0 - 20 °C

5.1: 98 percent / TEA / CH₂Cl₂ / 0 - 20 °C

6.1: 95 percent / TBAF / tetrahydrofuran / 2 h / 20 °C

7.1: 82 percent / PCC; 4 Angstroem molecular sieves / CH₂Cl₂ / 2 h / 20 °C

8.1: TiCl₄ / CH₂Cl₂ / 0.25 h / -78 °C

8.2: 95 percent / CH₂Cl₂ / 0.5 h / -78 °C

9.1: 66 percent / lithium aluminum hydride / diethyl ether / 0 - 20 °C

10.1: 90 percent / sodium hexamethyldisilazide / tetrahydrofuran; dimethylformamide / 0 - 20 °C

11.1: O₃ / CH₂Cl₂ / 0.17 h / -78 °C

11.2: 97 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

12.1: 97 percent / magnesium bromide etherate / CH₂Cl₂ / 1 h / 20 °C

13.1: O₃ / CH₂Cl₂ / 0.25 h / -78 °C

13.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

14.1: 851 mg / sodium borohydride / methanol / 0 - 20 °C

15.1: 92 percent / TEA / CH₂Cl₂ / 14 h / 0 °C

16.1: 89 percent / PPTS / benzene / 2 h / Heating

17.1: 90 percent / NaI / acetone / 2 h / Heating

18.1: 91 percent / n-Bu₃SnH; Et₃B; air / toluene; hexane / -78 °C

19.1: 100 percent / lithium borohydride / diethyl ether; tetrahydrofuran / 0 - 20 °C

20.1: 99 percent / I₂; triphenylphosphine; imidazole / tetrahydrofuran / 0 - 20 °C

21.1: 91 percent / dimethylformamide / 6 h / 20 °C

With 1H-imidazole; methanol; sodium tetrahydroborate; lithium aluminium tetrahydride; lithium borohydride; air; triethyl borane; 4 A molecular sieve; TEA; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; iodine; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; titanium tetrachloride; ozone; magnesium bromide ethyl etherate; triphenylphosphine; pyridinium chlorochromate; sodium iodide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; benzene; 4.1: Williamson ether synthesis;

DOI:10.1016/j.tet.2007.07.005

upstream raw materials:

C₂₃H₃₅IO₃

sodium benzenesulfonate

methanesulfonic acid 5-(1-methyl-2-oxo-ethyl)-tetrahydro-furan-2-ylmethyl ester

2-(5-methyl-tetrahydro-furan-2-yl)-hex-5-en-3-ol