trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate

Base Information

• Chemical Name: trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate
• CAS No.: 335672-87-2
• Molecular Formula: C₂₃H₂₅N₅O₅S
• Molecular Weight: 483.548
• Mol file: 335672-87-2.mol

Synonyms:trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate

Chemical Property of trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate

There total 2 articles about trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

sulfamethoxazole (723-46-6) + N-methyl-N-[2-(methacryloyloxy)ethyl]aniline (52234-98-7) → trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate (335672-87-2)

Guidance literature:

sulfamethoxazole; With hydrogenchloride; acetic acid; sodium nitrite;

N-methyl-N-[2-(methacryloyloxy)ethyl]aniline; In hydrogenchloride; 2-methoxy-ethanol; acetic acid;

Reference yield:

N-(2-hydroxyethyl)-N-methylaminobenzene (93-90-3) → trans-2-methyl-2-[4-({4-[(5-methylisoxazol-3-yl-amino)sulfonyl]phenyl}diazenyl)phenylamino]ethyl methacrylate (335672-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 4-(dimethylamino)pyridine; pyridine; BHT / 0.25 h / Heating

2.1: aq. HCl; AcOH; NaNO₂

2.2: 88 percent / 2-methoxy-ethanol; aq. HCl; acetic acid

With pyridine; hydrogenchloride; dmap; 2,6-di-tert-butyl-4-methyl-phenol; acetic acid; sodium nitrite;

upstream raw materials:

sulfamethoxazole

N-methyl-N-[2-(methacryloyloxy)ethyl]aniline

N-(2-hydroxyethyl)-N-methylaminobenzene