Didesmethylsibutramine hydrochloride, (R)-

Base Information

• Chemical Name: Didesmethylsibutramine hydrochloride, (R)-
• CAS No.: 262854-35-3
• Molecular Formula: C₁₅H₂₂ClN*ClH
• Molecular Weight: 288.26
• UNII: YWP9I7EXUM
• Wikidata: Q27294751
• Mol file: 262854-35-3.mol

Synonyms:262854-35-3;YWP9I7EXUM;Didesmethylsibutramine hydrochloride, (R)-;UNII-YWP9I7EXUM;((R)-1-(1-(4-Chlorophenyl)cyclobutyl)-3-methylbutan-1-yl)amine hydrochloride;(1R)-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine;hydrochloride;Didesmethyl (alphaR)-Sibutramine Hydrochloride;Cyclobutanemethanamine, 1-(4-chlorophenyl)-alpha-(2-methylpropyl)-, hydrochloride, (alphaR)-;Cyclobutanemethanamine, 1-(4-chlorophenyl)-alpha-(2-methylpropyl)-, hydrochloride (1:1), (alphaR)-;(R)-didesmethylsibutramine hydrochloride;Q27294751;CYCLOBUTANEMETHANAMINE, 1-(4-CHLOROPHENYL)-.ALPHA.-(2-METHYLPROPYL)-, HYDROCHLORIDE (1:1), (.ALPHA.R)-;CYCLOBUTANEMETHANAMINE, 1-(4-CHLOROPHENYL)-.ALPHA.-(2-METHYLPROPYL)-, HYDROCHLORIDE, (.ALPHA.R)-

Chemical Property of Didesmethylsibutramine hydrochloride, (R)-

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 287.1207551
• Heavy Atom Count: 18
• Complexity: 239

Purity/Quality:

Didesmethyl(αR)-SibutramineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N.Cl
• Isomeric SMILES: CC(C)C[C@H](C1(CCC1)C2=CC=C(C=C2)Cl)N.Cl
• Uses: Didesmethyl (αR)-Sibutramine Hydrochloride is a metabolite of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.

Technology Process of Didesmethylsibutramine hydrochloride, (R)-

There total 1 articles about Didesmethylsibutramine hydrochloride, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H24ClNO → (R)-di-des-methylsibutramin hydrochloride (262854-35-3) + di-desmethylsibutramine hydrochloride (262854-36-4)

Guidance literature:

With hydrogenchloride; water; at 20 - 180 ℃; for 21.5h; under 2250.23 - 33003.3 Torr;

Refernces