Menogaril

Base Information

Chemical Name:Menogaril
CAS No.:71628-96-1
Deprecated CAS:69256-91-3,74202-31-6
Molecular Formula:C₂₈H₃₁NO₁₀
Molecular Weight:541.555
Hs Code.:
UNII:8JSV4O30HQ
DSSTox Substance ID:DTXSID601024504
Nikkaji Number:J59.177G
Wikipedia:Menogaril
Wikidata:Q6817231
NCI Thesaurus Code:C1389
ChEMBL ID:CHEMBL1234391
Mol file:71628-96-1.mol

Synonyms:7-con-O-Methylnogarol;7-O-Methylnogarol;7-OMEN;Menogaril;Menogaril, (11 beta)-Isomer;Menogaril, (13 beta)-Isomer;Menogaril, (5 alpha)-Isomer;Menogaril, (5 alpha,11 beta)-Isomer;Menogarol;NSC 269148;NSC-269148;NSC269148;Tomosar;TUT 7;TUT-7;TUT7

Suppliers and Price of Menogaril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MENOGARIL 95.00%
5MG
$ 503.71

Total 4 raw suppliers

Chemical Property of Menogaril

Chemical Property:

Vapor Pressure:5.17E-27mmHg at 25°C
Melting Point:247-249° (dec); mp 250-254° (dec)
Refractive Index:1.6290 (estimate)
Boiling Point:800.1°C at 760 mmHg
Flash Point:437.7°C
PSA：166.22000
Density:1.59g/cm³
LogP:0.87380
XLogP3:0.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:2
Exact Mass:541.19479619
Heavy Atom Count:39
Complexity:1020

Purity/Quality:

99% ^*data from raw suppliers

MENOGARIL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(C2=C(C3=C(C=C2C1)C(=O)C4=C5C(=CC(=C4C3=O)O)C6(C(C(C(C(O5)O6)O)N(C)C)O)C)O)OC)O
Isomeric SMILES:C[C@@]1(C[C@H](C2=C(C3=C(C=C2C1)C(=O)C4=C5C(=CC(=C4C3=O)O)[C@@]6([C@@H]([C@H]([C@@H]([C@H](O5)O6)O)N(C)C)O)C)O)OC)O
Uses Antineoplastic.

Technology Process of Menogaril

There total 1 articles about Menogaril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 135708-65-5
C₃₆H₄₇NO₁₄

: 64267-47-6,71628-96-1,105119-19-5,111688-19-8,114926-58-8,118473-59-9,135818-55-2
7-con-O-methylnogarol

Guidance literature:: With hydrogenchloride; In acetic acid; at 45 ℃; for 4h;
DOI:10.1021/jo00018a006

Reference yield: 33.0%

: 288-32-4
1H-imidazole

: 64267-47-6,71628-96-1,105119-19-5,111688-19-8,114926-58-8,118473-59-9,135818-55-2
menogaril

: 71582-53-1,113532-66-4,116838-50-7
7-deoxynogarol

: 123206-66-6,123285-66-5
7-imidazoyl-7-deoxynogarol

: 123206-66-6,123285-66-5
7-imidazoyl-7-deoxynogarol

Guidance literature:: With 5,5'-bis(hydroxymethyl)-3,3',5,5'-tetramethyl-3,3'-bimorpholine-2,2'-dione; In N,N-dimethyl-formamide; at 25 ℃; for 72h; Yields of byproduct given;
DOI:10.1021/jo00282a024